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Elaine Marzluff
Associate Professor of Chemistry

Elaine Marzluff Office: S 2208
Phone: 641-269-4314
Email: marzluff@grinnell.edu


A.B. (with high honors in Chemistry), 1989, Harvard University.
Ph.D. (Chemistry), 1995, California Institute of Technology.

Research
Professor Marzluff is interested in the structure and dissociation mechanisms and energetics of peptides and proteins in the gas phase. She couples electrospray ion trap mass spectrometry with collisional activated dissociation and Hydrogen Deuterium exchange reactions to probe the gas phase structure of biological molecules. Her research also focuses on the fundamental issues associated with the activation and dissociation dynamics of large molecules in the gas phase.

[Full description PDF]

Courses
  • CHM 129 General Chemistry
  • CHM 130 Inorganic & Analytical Chemistry
  • CHM 363 Physical Chemistry I
  • CHM 364 Physical Chemistry II
  • CHM 390 Seminar: Current Topics in Chemistry
Recent Publications
(Undergraduate co-authors underlined.)
  • T. D. Vaden, T. S. J. A. de Boer, N. A. MacLeod, E. M. Marzluff, J. P. Simons and L. C. Snoek “Infrared spectroscopy and structure of photochemically protonated biomolecules in the gas phase: a noradrenaline analogue, lysine and alanyl alanine” Phys. Chem. Chem. Phys., 2007, 9, 2549–2555.

  • Hünig, I; Painter, A.J.; Jockusch, R.A.; Çarçabal, P.; Marzluff, E.M.; Snoek, L.C.; Gamblin, D.P.; Davis, B.G.; Simons, J.P. “Adding water to sugar: A spectroscopic and computational study of alpha- and beta-phenylxyloside in the gas phase” Phys. Chem. Chem. Phys., 2005, 7, 2474 – 2480.

  • “Gas Phase H/D Exchange of Small Protonated Peptides: Side Chain Effects” Elaine M. Marzluff, Joe Jankolovits, Spring Knapp, Masayo Ozaki and Michael B. Satzer, presented at the “Gaseous Ions” Gordon Research Conference, Ventura, CA, Feb 25-Mar 2, 2007.

  • “Gas Phase Hydrogen Deuterium Exchange of Peptides: Implications for Protein Structure Determination” Elaine M. Marzluff, Michael B. Satzer, Katherine A. Hodes, Elizabeth Moscato, Desire Takawira and Masayo Ozaki, presented at the conference on “Isolated Biomolecules and Biomolecular Interaractions” May 9-14, 2006, Trest Castle, Czech Republic.

  • Evans, S.E.; Lueck, N.; Marzluff, E. M. “Gas Phase H/D Exchange of Proteins in an Ion Trap Mass Spectrometer” International Journal of Mass Spectrometry, 2003, 222, 175-187.


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