| 2008 | Robert H. Grubbs | Calif. Inst. of Technology | Design of efficient olefin metathesis catalysts (lecture for chemistry students); Where fundamental chemistry can take you: Following the Olefin metathesis (lecture for general public) |
| 2006 | Peter C. Agre | Duke Univ. Medical Center | Seminar: Blueprints for Cellular Plumbing System; Convocation: My Life in Science: From Lake Wobegone to Stockholm; and HHMI Symposium Keynote Lecture: Aquaporin Water Channels - The Nobel Lecture |
| 2004 | Stephen Lippard | Mass. Inst. of Technology | Seminar: Hydrocarbon Oxidation at Non-Heme Iron Centers; and Convocation: Platinum Complexes: From DNA Damage to Curing Cancer |
| 2002 | K. Barry Sharpless | Scripps Research Inst. | An Asymmetric Odyssey Leading Back to Its Port of Origin |
| 2001 | Jesse L. Beauchamp | Calif. Inst. of Technology | Countering Terrorism: Scientific and Technological Challenges |
| 2001 | Mario Molina | Mass. Inst. of Technology | The Antarctic Ozone Hole |
| 2000 | Cynthia Friend | Harvard University | Science and Technology in Society |
| 1999 | Doug P. Blanchard | NASA | (CREATION)2: LIFE ON MARS |
| 1997 | Peter Kollman ('66) | University of CA, SF | Computer Modeling in Physics, Chemistry, and Biology: Both Numbers and Beautiful Pictures Give Lots of Insight |
| 1996 | Dean Martin ('55) | U. of South Florida | Malthusian vs. Cornucopean Views of the Environment |
| 1995 | Carl Djerassi | Stanford Univ. | Birth Control in the Year 2001 |
| 1994 | Jacqueline Barton | Calif. Inst. of Technology | Travels Along the DNA Helix |
| 1993 | Margaret A. Tolbert ('79) | U. of Colorado | Stratospheric Ozone Depletion at the Ends of the Earth and In Between |
| 1992 | Shirley Malcom | Amer. Assoc. for the Advancement of Science | Science: Making New Connections |
| 1991 | Bassam Shakhashiri | U. of Wisconsin | Enhancing the Quality of Education in America |
| 1990 | R. Stephen Berry | U. of Chicago | Guiding Policy for a Technological Future |
| 1988 | Clair Patterson ('43) | Calif. Inst. of Technology | Effects of 7000 Years of Lead Technology on Human Cultures and Health |
| 1987 | Alfred Bader | Sigma Aldrich Co. | The Bible Through Dutch Eyes |
| 1986 | Thomas R. Cech ('70) | U. of Colorado | Catalysis by RNA |
| 1985 | George G. Hammond | Allied Chemical | Flexibility of Scientific Dillettantism |
| 1984 | Melvin Calvin | U. of California | Energy Agriculture |
| 1983 | Derek Davenport | Purdue Univ. | The Relative Unimportance of the Invective Effect in Physical Organic Chemistry |
| 1982 | Mary Good | Universal Oil Products, Inc. | Science and Society |
| 1981 | Herbert C. Brown | Purdue Univ. | From Little Acorns to Tall Oaks - From Boranes through Organoboranes |
| 1980 | Thomas Lippincott | U. of Arizona | The Boltzmann Distribution |
